中国癌症杂志 ›› 2015, Vol. 25 ›› Issue (2): 155-160.doi: 10.3969/j.issn.1007-3969.2015.02.013

• 综述 • 上一篇    

乳腺癌的相关受体表达差异及进展

李立立 综述 姜达 审校   

  1. 河北医科大学第四医院肿瘤内科,河北 石家庄 050035
  • 出版日期:2015-02-28 发布日期:2015-05-13
  • 通信作者: 姜达 E-mail:jiangda139@163.com

The expression differences and their significance of the relevant receptors in breast cancer

LI Lili, JIANG Da   

  1. Department of Medical Oncology, the 4th Hospital, Hebei Medical University, Shijiazhuang Hebei 050035, China
  • Published:2015-02-28 Online:2015-05-13
  • Contact: JIANG Da E-mail: jiangda139@163.com

摘要:      ER、PR、HER-2在乳腺癌中是指导治疗和判断预后的重要的生物学标志物。随着乳腺癌的病情进展,ER、PR、HER-2的表达在原发灶及转移灶中可能存在差异。目前临床医师已意识到对转移灶进行受体检测的必要性。该文结合目前的研究现状就上述问题进行综述。

关键词: 乳腺癌, 受体, 表达

Abstract:           ER, PR, HER-2 are significant biological markers in guiding the choice of treatment and evaluating clinical prognosis. As the progression of tumor cells, the expressions of these receptors in recurrent tumors may be ifferent from primary tumors. Nowadays clinicians have realized the necessity of receptor detection in the metastatic lesions. This article summarized the current research status on the above issues.

Key words:  Breast cancer, Receptor, Expression