中国癌症杂志 ›› 2018, Vol. 28 ›› Issue (2): 140-145.doi: 10.19401/j.cnki.1007-3639.2018.02.010

• 论著 • 上一篇    下一篇

单中心乳腺癌术后乳房重建的影响因素

马林晓曦,黄乃思,郭 亮,曹阿勇,柳光宇,胡 震, 狄根红,沈镇宙,邵志敏,吴 炅   

  1. 复旦大学附属肿瘤医院乳腺外科,上海市乳腺肿瘤重点实验室,复旦大学上海医学院肿瘤学系,上海 200032
  • 出版日期:2018-02-28 发布日期:2018-03-08
  • 通信作者: 吴 炅 E-mail:wujiong1122@vip.sina.com

Relationship between breast reconstruction and travel distance

MA Linxiaoxi, HUANG Naisi, GUO Liang, CAO Ayong, LIU Guangyu, HU Zhen, DI Genhong, SHEN Zhenzhou, SHAO Zhimin, WU Jiong   

  1. Department of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
  • Published:2018-02-28 Online:2018-03-08
  • Contact: WU Jiong E-mail: wujiong1122@vip.sina.com

摘要: 背景与目的:乳腺癌手术方式的选择受到诸多因素影响,本研究旨在分析乳腺癌患者选择乳房重建手术的影响因素,重点探讨居住地距离与乳房重建的关系。方法:回顾性分析了1999年1月—2015年12月复旦大学附属肿瘤医院收治的因单侧或双侧0~Ⅱ期乳腺癌行全乳切除术的女性患者临床资料,分析居住地距离与乳房重建比例的关系。结果:非上海患者选择全乳切除术后乳房重建比例高于上海患者(6.1% vs 4.5%,P<0.001)。居住地距离影响乳房重建比例(P=0.035)。单因素分析显示,居住地距离越远,选择乳房重建手术比例越高,而年龄、体质量指数(body mass index,BMI)、TNM分期与乳房重建的选择呈负相关(P均<0.001)。多因素分析显示,年龄增长、BMI增加、TNM分期较晚是拒绝行乳房重建的独立影响因素(P均<0.001),而居住地距离不是乳房重建的独立影响因素(P>0.05),且与具体乳房重建方式无交互作用。年龄与居住地距离呈负相关(P<0.001)。结论:乳腺癌患者的居住地距离与乳房重建比例呈线性相关;年龄、BMI和疾病分期是影响乳房重建的主要因素。

关键词: 居住地距离, 乳房重建, 乳腺癌

Abstract: Background and purpose: Many factors have impacts on the surgery approach of breast cancer. The purpose of this study was to analyze the influence factors of breast reconstruction for patients with breast cancer, focusing on the relationship between travel distance and breast reconstruction. Methods: Retrospective review of all female breast cancer patients staging 0-Ⅱ who underwent unilateral or bilateral mastectomy with or without breast reconstruction at Fudan University Shanghai Cancer Center from 1999 to 2015 was conducted in the study. Analysis of travel distance and breast reconstruction rate was performed. Results: Non-Shanghai patients have higher breast reconstruction rate after mastectomy compared with Shanghai patients (6.1% vs 4.5%, P<0.001). Travel distance may have an influence on the breast reconstruction rate (P=0.035). Univariate regression analysis showed that the increase of travel distance was the predictor of breast reconstruction, and that the increase of age or body mass index (BMI), or the later TNM stage had a negative correlation with breast reconstruction (P<0.001). Multiple regression analysis demonstrated that the increase of age or BMI, or the later TNM stage was the independent predictor of the refusal of breast reconstruction (P<0.001), but travel distance was not (P>0.05). No significant correlation between the travel distance and breast reconstruction types was indicated. Negative correlation was observed between age and travel distance (P<0.001). Conclusion: Age, BMI and tumor stage are the main influence factors of breast reconstruction, while travel distance shows a linear correlation with it.

Key words: Travel distance, Breast reconstruction, Breast cancer