China Oncology ›› 2020, Vol. 30 ›› Issue (10): 726-732.doi: 10.19401/j.cnki.1007-3639.2020.10.002

• Specialists’ Commentary and Article • Previous Articles     Next Articles

Lung cancer screening strategy for non-high-risk population 

ZHOU Yaodong 1, 2, 3 , CHEN Zongwei 3, 4 , CHEN Haiquan 1, 2, 3   

  1. 1. Department of Thoracic Surgery, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China; 2. Key Laboratory of Genetic Engineering, Shanghai 200032, China; 3. Institute of Thoracic Cancer of Fudan University, Shanghai 200032, China; 4. Department of Thoracic Surgery, Zhongshan Hospital Fudan University, Shanghai 200032, China
  • Online:2020-10-30 Published:2020-11-11
  • Contact: CHEN Haiquan E-mail: hqchen1@yahoo.com

Abstract: Low-dose spiral computed tomography (LDCT) screening for lung cancer reduced mortality in high-risk groups by 20.0%. The current screening criteria for high-risk groups have limitations and cannot be applied to non-high-risk groups. New specific screening strategies are needed. Now some companies put lung cancer CT screening as a benefit, regardless of age and other factors to do once a year, which is not only a waste of medical resources, but also harmful to physical and mental health. It is recommended to advance the time of the first baseline LDCT to near the age of 30 years, and to extend the follow-up interval from 2 to 10 years according to the findings of baseline CT combined with different age groups and other risk factors. A compromise screening strategy should be adopted for non-high-risk groups to detect lung cancer early and reduce CT radiation exposure.

Key words: Low-dose spiral computed tomography, Lung cancer, Non-high-risk population, Non-smokers, Indolent