China Oncology ›› 2014, Vol. 24 ›› Issue (4): 316-320.doi: 10.3969/j.issn.1007-3969.2014.04.013

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Progress on chemotherapy for triple negative breast cancer

NI Chen, LI Ting, WU Zhen-hua, HU Xi-chun   

  1. Department of Medical Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
  • Online:2014-04-30 Published:2014-05-06
  • Contact: HU Xi-chun E-mail: xchu2009@hotmail.com

Abstract:

Triple negative breast cancer (TNBC), as a special molecular subtype of breast cancer, is nonresponsive to endocrine therapy or commercially available targeted therapy. It is characterized by early recurrence, rapid progression and poor prognosis. This systemic and comprehensive overview was focused on recent progress on molecular subtyping of triple negative breast cancer and its possible clinical value, chemotherapeutic agents and chemotherapy regimens, and combination of chemotherapy with potential molecular targeting agents.

Key words: Triple negative breast cancer, Molecular subtypes, Neoadjuvant chemotherapy, Adjuvant chemotherapy, Palliative chemotherapy