Abstract: Cancer has become one of the most important public issues which seriously influence the health condition of Chinese population. The cancer-related fatigue has drawn great attention. Studies have reported that cancer-related fatigue is the most common concomitant symptom of cancer. Cancer-related fatigue could negatively affect the work, social relationship, emotions, daily activities and quality of life of cancer patients, leading to discontinuation of the treatment and even influencing the time of survival in cancer patients. However, there is no relevant guideline to instruct the clinical diagnosis and treatment of cancer-related fatigue in China. Experts and scholars from the Tumor Support and Rehabilitation Therapy Group, the Oncology Committee of Chinese Medical Association summarized the research progress of cancer-related fatigue so as to transmit important information and guide clinical practice timely. This guideline mainly covers the definition, epidemiology, clinical manifestations, pathogenesis, interfering factors, types of Traditional Chinese Medicine syndrome, screening, clinical evaluation and integrative Traditional Chinese Medicine and Western medicine treatment, aiming to provide suggestions for the clinical diagnosis and treatment of cancer-related fatigue, to facilitate the promotion of standardized treatment for patients with cancer-related fatigue, and to improve the clinical prognosis of patients with cancer-related fatigue.

Key words: Cancer-related fatigue, Clinical practice, Diagnosis and treatment, Guideline