Research progress of DNA methylation in thyroid cancer

doi:10.19401/j.cnki.1007-3639.2017.04.011

Welcome to China Oncology,

China Oncology ›› 2017, Vol. 27 ›› Issue (4): 304-311.doi: 10.19401/j.cnki.1007-3639.2017.04.011

Previous Articles Next Articles

Research progress of DNA methylation in thyroid cancer

CAO Yiming, ZHU Yongxue

Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China

Online:2017-04-30 Published:2017-05-05
Contact: ZHU Yongxue E-mail: zhuyongxue163@126.com

Share article

Abstract

Abstract: DNA methylation is an important epigenetic modification. Evaluating the status of DNA methylation could be useful for diagnosis, prognostic evaluation and predicting the risk of cancer. Thyroid cancer is the most prevalent endocrine malignancy in humans. Growing evidence shows that epigenetic abnormalities participate with genetic alterations in carcinogenesis of thyroid cancer. This article reviewed the recent research progress of DNA methylation in thyroid cancer.

Key words: Thyroid cancer, Epigenetics, DNA methylation

CAO Yiming, ZHU Yongxue. Research progress of DNA methylation in thyroid cancer[J]. China Oncology, 2017, 27(4): 304-311.

[1]	XU Ziqi, HU Ruizhi, LI Junjian, WANG Hongxia, SANG Youzhou. Exploring the role of methylation-driven gene IFFO1 in pancreatic adenocarcinoma diagnosis, prognosis and cellular functions [J]. China Oncology, 2024, 34(11): 998-1010.
[2]	XUE Liqiong, GUO Ye, CHEN Libo. Expert consensus on the management of adverse events in patients receiving targeted agents for advanced thyroid cancer (2023 edition) [J]. China Oncology, 2023, 33(9): 879-888.
[3]	YUAN Xinyue, YAO Yao, CHENG Shuai, ZHENG Xin, ZHANG Yuan. Clinical study on high-risk factors for contralateral lymph node metastasis in unilateral papillary thyroid carcinoma [J]. China Oncology, 2023, 33(6): 619-628.
[4]	QU Ning, WANG Yuting, MA Ben, WANG Yu. Advances in basic research, clinical diagnosis and treatment of thyroid cancer in 2022 [J]. China Oncology, 2023, 33(5): 423-430.
[5]	SUN Di, SUN Yuqing, ZHANG Xin, HUANG Lisha, LIN Yansong. The relationship between genetic characteristics and clinical characteristics and the efficacy of ¹³¹I therapy in children and adolescents with locally advanced or metastatic differentiated thyroid cancer [J]. China Oncology, 2022, 32(5): 380-387.
[6]	DENG Shuting, FENG Yuan, QIAN Kai, GUO Kai, WANG Zhuoying. Meta-analysis of the association between gene alterations and distant metastasis of differentiated thyroid carcinoma in children and adolescents [J]. China Oncology, 2022, 32(5): 388-396.
[7]	LIU Jia, LI Guanghan, GAO Luying, ZHANG Zijie, WANG Ying, XIONG Ying, ZHANG Bo. Establishment and test of graded diagnostic model of thyroid cancer in children and adolescents [J]. China Oncology, 2022, 32(5): 397-403.
[8]	GUO Wenting, MU Zhuanzhuan, LI Zheng, ZHANG Yingqiang, JIN Xiaona, LIN Yansong. Clinical outcome of ¹³¹I therapy in differentiated thyroid cancer patients with suspicious high thyroglobulin concentration [J]. China Oncology, 2022, 32(5): 410-416.
[9]	MEI Xiaoran, FENG Fang, WANG Hui, WEI Zhixiao. Analysis of therapeutic response of iodine positive metastasis lymph nodes in differentiated thyroid cancer after ¹³¹I treatment [J]. China Oncology, 2022, 32(11): 1091-1097.
[10]	CHEN Guo , HAN Pengli , CHEN Keru , LI Mingchuang , ZHANG Qingsong , CHEN Zheng , DONG Hanhua , QIAN Yuejun , LÜ Jing . Molecular mechanism of miR-19b-3p regulating apoptosis of medullary thyroid cancer cells by targeting MTUS1 [J]. China Oncology, 2021, 31(5): 390-396.
[11]	YUAN Hao , JIANG Xiaofei , YOU Qinghua , ZHU Hongbo , YE Huiying , WU Wen , QIAN Fengyuan , ZHONG Ming , LI Yongping . Clinical application of fine needle puncture Diff-Quik staining for the differentiation and protection of parathyroid glands in thyroid carcinoma surgery [J]. China Oncology, 2021, 31(4): 302-307.
[12]	WU Yuanyuan , WANG Jun , LIU Qinjiang , ZHANG Ming . Analysis of prognostic factors and treatment strategies of anaplastic thyroid carcinoma [J]. China Oncology, 2021, 31(3): 212-220.
[13]	WU Hongwen, MEI Yan, WANG Qiao, YUAN Jia, ZHAO Liwei. The clinical value of serum MIP-1α and S-TK1 in the evaluation of postoperative radioactive ¹³¹ I treatment for thyroid carcinoma [J]. China Oncology, 2021, 31(11): 1088-1095.
[14]	LI Min, WEN Peng, QIAN Qiuqin, QIN Ang, ZENG Li, SHI Feng. Clinical study of iodine-125 seeds implantation in the treatment of lymph node metastasis of radioactive iodine- refractory differentiated thyroid cancer [J]. China Oncology, 2020, 30(2): 122-127.
[15]	MU Zhuanzhuan , LI Zheng , ZHANG Xin , LIN Yansong . The effect of empiric ¹³¹ I therapy in papillary thyroid cancer patients with pulmonary metastasis [J]. China Oncology, 2020, 30(12): 991-995.

Research progress of DNA methylation in thyroid cancer

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments