China Oncology ›› 2015, Vol. 25 ›› Issue (11): 877-889.doi: 10.3969/j.issn.1007-3969.2015.11.007

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Advances in chemotherapy for advanced colorectal cancer

LI Wenhua, ZHANG Wen   

  1. Department of Medical Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
  • Online:2015-11-30 Published:2016-02-01
  • Contact: ZHANG Wen E-mail: zw65242@163.com

Abstract: Chemotherapy is the main treatment approach for advanced colorectal cancer. The 5-fluorouracil (5-FU), oxaliplatin and irinotecan are three major chemotherapeutic drugs. The combined chemotherapy and “stop and go” treatment mode increase the efficacy and patients’ tolerance. The new drugs, raltitrexed, S-1 and TAS-102, have been approved for use in cancer treatment. This article reviews the new development in chemotherapy for the treatment of advanced colorectal cancer.

Key words: Colorectal cancer, Chemotherapy, Metastases