China Oncology ›› 2018, Vol. 28 ›› Issue (1): 75-80.doi: 10.19401/j.cnki.1007-3639.2018.01.011

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Prevention strategy of cardiotoxicity in cancer chemotherapy

HAN Jinbin1, WU Ning2, HUA Yongqiang3, ZHU Fu4   

  1. 1. Department of Traditional Chinese Medicine, Shanghai Ninth people's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200033, China; 2. Department of Oncology, Gongli Hospital of Shanghai Pudong New District, Shanghai 200135, China; 3. Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China; 4. Department of Cardiology, Central Hospital of Shanghai Xuhui District, Shanghai 200031, China
  • Online:2018-01-30 Published:2018-02-07
  • Contact: ZHU Fu E-mail: zhufu@xh.sh.cn

Abstract: The cardiotoxicity of chemotherapeutic drugs is receiving more and more attention. The incidence and severity of cardiotoxicity can be reduced by methods such as reducing the dose of drugs, adjusting administration, and using low toxic drugs in clinical practice. Besides, appLncation of cardioprotective agents is very important and agents including cardiovascular ones, dexrazoxane as well as Chinese medicine preparations are commonly used currently. However, effects of these agents used for cardioprotection during chemotherapy are limited, and their safety needs further verification.

Key words: Cardio-oncology, Cardiotoxicity, Chemotherapy, Dexrazoxane