Abstract:

Breast cancer stem cells comprise a sub-population, which enables the capacity for self-renewal and the potentiality for differentiation and high tumorigenicity. Growing evidence suggests that breast cancer stem cells most likely contribute to tumor generation, progression, relapse, metastasis and therapeutic resistance. Herein, the recent advances in breast cancer stem cells were highlighted in this review.

Key words: Breast cancer, Stem cell, Signaling pathway, miRNA