China Oncology ›› 2022, Vol. 32 ›› Issue (8): 680-687.doi: 10.19401/j.cnki.1007-3639.2022.08.002
• Specialists' Commentary • Previous Articles Next Articles
QIU Pengfei()(), WANG Yongsheng()()
Received:
2022-06-10
Revised:
2022-07-15
Online:
2022-08-30
Published:
2022-09-19
Contact:
WANG Yongsheng
E-mail:qiupengfei2002@126.com;wangysh2008@aliyun.com
CLC Number:
QIU Pengfei, WANG Yongsheng. Precise regional management of breast cancer in the sentinel lymph node era: evolution and prospect[J]. China Oncology, 2022, 32(8): 680-687.
Tab. 1
Survival benefit of IMLN radiotherapy"
Item | French (n=1 334) | EORTC 22922/10925 (n=4 004) | MA.20 (n=1 832) | DBCG-IMN (n=3 089) |
---|---|---|---|---|
Recruitment years | 1991-1997 | 1996-2004 | 2000-2007 | 2003-2007 |
Follow-up years (median) | 11.3 | 15.7 | 9.5 | 14.8 |
Proportion of positive axillary node | 75.2% | 55.5% | 90.3% | 100.0% |
Proportion of adjuvant systemic therapy | Chemotherapy 60.9% Endocrine therapy 52.3% | 84.4% | 100.0% | 100.0% |
Breast cancer recurrence | 43.1% vs 50.3% | 24.5% vs 27.1% Δ | NA | NA |
Breast cancer mortality | NA | 16.0% vs 19.8% Δ | 10.3% vs 12.3% | 31.7% vs 33.9%Δ |
Distant disease-free survival | NA | 70.0% vs 68.2% | 86.3% vs 82.4%Δ | 64.4% vs 61.4%Δ |
DFS | 53.2% vs 49.9% | 60.8% vs 59.9% | 82.0% vs 77.0%Δ | NA |
OS | 62.6% vs 59.3% | 73.1% vs 70.9% | 82.8% vs 81.8% | 60.1% vs 55.4%Δ |
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