China Oncology ›› 2020, Vol. 30 ›› Issue (9): 701-706.doi: 10.19401/j.cnki.1007-3639.2020.09.010
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PAN Xinghao, LIU Mingbin, ZHANG Xiaoyan, XU Jianqing
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Abstract: Exosomes are nanoscale vesicles derived from the inner membrane of cells, containing life information such as nucleic acids, proteins and lipids. They play an important role in life activities as a mechanism of intercellular communication. Compared to liposome carriers, exosomes are more stable, biocompatible and less immunogenic, and can penetrate biological barriers such as the blood-brain barrier and the placental barrier. This article focused on the basis of exosome vector targeting, the method of carrier loading and the current application progress and prospects.
Key words: Exosomes, Targeting, Therapeutic vector
PAN Xinghao, LIU Mingbin, ZHANG Xiaoyan, XU Jianqing. Advances in research of exosomes as targeted therapeutic vectors[J]. China Oncology, 2020, 30(9): 701-706.
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URL: http://www.china-oncology.com/EN/10.19401/j.cnki.1007-3639.2020.09.010
http://www.china-oncology.com/EN/Y2020/V30/I9/701