Abstract:

Background and purpose: Ductal carcinoma in situ (DCIS), is precursor lesions of invasive breast cancer, belongs to non-systemic ductal lesions, which is similar to other ductal lesions on imaging. This study aimed to investigate the differential diagnostic value of MRI in DCIS between DCIS with microinvasion (DCIS-MI) and breast intraductal papilloma (BIDP). Methods: All the cases were surgico-pathologically confirmed. Twenty-four patients were DCIS, 9 patients were DCIS-MI, and 20 patients were BIDP. The MRI charateristics of DCIS, DCIS-MI and BIDP were analyzed and compared. Results: DCIS and DCIS-MI’s performance in the form of MRI is difficult to differentiate (P<0.05). Compared with BIDP, the ductal and segmental enhancement, type Ⅲ time-signal intensity curve (TIC), and the red pseudo-color image were associated with the DCIS. The local area enhancement, type Ⅱ TIC, and no-red pseudo-color image were associated with BIDP. Conclusion: MRI is a useful for differentiate between DCIS and BIDP, but is difficult for DCIS and DCIS-MI.

Key words: Breast, Ductal carcinoma in situ, MRI, Diagnosis