Abstract: Pancreatic cancer is a highly lethal disease in gastrointestinal malignant tumors. The prognosis of patients with pancreatic cancer is poor, due to the rapid progression, lack of early diagnosis, low surgical resection rate and inefficiency of chemotherapy. The incidence of pancreatic cancer has increased significantly in the recent years. As the understanding of tumor behavior deepens, the basic research navigates new routes for clinical treatment and enriches clinical methods. Pancreatic cancer treatment has been transitioned from “surgery first” to multidisciplinary collaborative treatment team (MDT) models. In this review, we summarized recent high quality studies on pancreatic cancer including epidemiological investigation, pathogenic factor, advances in basic research, and clinical treatment.

Key words: Pancreatic cancer, Epidemiology, Basic research, Clinical research, Progress