Abstract: Pancreatic cancer is a highly malignant tumor of the digestive system. Due to the lack of early diagnosis, rapid disease progression and unsatisfactory chemotherapy effectiveness, the prognosis of patient is extremely poor with an overall 5-year survival rate of 8%. In recent years, with the changes in residents’ dietary habits and lifestyles, the incidence of pancreatic cancer has increased year by year, which seriously threatens the health of the people. With continuous research and efforts, our understanding of the biological behavior and clinical diagnosis and treatment of pancreatic cancer have been continuously improved. The treatment mode of pancreatic cancer has also transitioned from the purely surgical or chemical treatment in the past to a comprehensive treatment model based on multiple disciplinary teams. Here we reviewed the latest high quality studies published in 2019, and summarized the progress of pathogenesis, basic and clinical research on pancreatic cancer to provide theoretical support for conquering this lethal disease.

Key words: Pancreatic cance, Epidemiology, Basic research, Clinical research, Progress