China Oncology ›› 2023, Vol. 33 ›› Issue (3): 235-240.doi: 10.19401/j.cnki.1007-3639.2023.03.006

• Specialists' Commentary • Previous Articles     Next Articles

Leading research progress and prospect of antibody-drug conjugate in pancreatic cancer in 2022

ZENG Cheng(), ZHANG Jian()   

  1. Phase Ⅰ Clinical Trial Center, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
  • Received:2023-01-30 Revised:2023-02-23 Online:2023-03-30 Published:2023-04-17
  • Contact: ZHANG Jian

Abstract:

Pancreatic cancer is a type of malignant tumor with high incidence and low survival rate. It is urgent to develop novel and efficient therapeutic means for patients lacking surgical indications and patients with poor effects of radiotherapy and chemotherapy. In recent years, antibody-drug conjugate (ADC) has become hot because of their high selectivity and anti-tumor activity. ADC has achieved some results in the treatment of pancreatic cancer, but still face many challenges. This article provided a brief review of the latest developments of ADC in pancreatic cancer in 2022.

Key words: Antibody-drug conjugate, Pancreatic cancer, Clinical research

CLC Number: