China Oncology ›› 2014, Vol. 24 ›› Issue (10): 727-731.doi: 10.3969/j.issn.1007-3969.2014.10.002

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Multiple myeloma: from diagnosis to staging

YANG Rui-xue, GAO Lu, SHI Ju-mei   

  1. Department of Hematology, Tenth People’s Hospital of Tongji University, Shanghai 200072, China
  • Online:2014-10-30 Published:2014-11-12
  • Contact: SHI Ju-mei E-mail: shijumei@hotmail.com

Abstract:

Multiple myeloma (MM) is a plasma cell malignancy. With the development of the understanding of MM, the diagnosis is no more limited to bone marrow biopsy and imageological examination. Serum free light chain, cytogenetic analysis and molecular biology study are becoming increasingly widely used, which give us a deeper understanding of the mechanisms of MM and provide us with a clearer prognosis evaluation. Here is to make a review of the diagnosis and its development of MM from laboratory examination, diagnosis criteria and classification.

Key words: Multiple myeloma, Diagnosis, Stage