China Oncology ›› 2014, Vol. 24 ›› Issue (11): 865-870.doi: 10.3969/j.issn.1007-3969.2014.11.012

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The related mechanism of radiotherapy in triple-negative breast cancer

LI Bing-xin1, FU Shen2   

  1. 1.Department of Radiation Oncology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 200032, China; 2. Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Shanghai 201321, China
  • Online:2014-11-30 Published:2015-05-05
  • Contact: FU Shen E-mail: shen_fu@hotmail.com

Abstract: Radiotherapy is one of the main means of local treatment of breast cancer. Triple negative breast cancer (TNBC) as a molecular subtypes of breast cancer, its biological behavior is special and existing multiple molecular targets, these molecular targets influence the response of ionization radiation through different mechanisms and regulate radiotherapy sensitivity of TNBC This article reviewed the recent advances in radiotherapy and radiosensitivity related molecular targets of TNBC.

Key words: Triple-negative breast cancer, Radiotherapy, Radiosensitivity, Biomarker