Abstract: Background and purpose: Breast cancer is one of the major chronic diseases affecting adult women. The incidence of breast cancer in China is increasing at a rate of 3%-4% per year, which seriously endangers women's health. Therefore, it is necessary to explore the application of ultrasound screening mode in primary hospitals and the feasibility and application value of ultrasound screening as an early detection and diagnosis method for breast cancer in primary hospitals. Methods: Breast cancer screening based on breast ultrasonography was used to select women aged from 35 to 60 years in the Hami area to undergo the screening for breast cancer. All women underwent breast ultrasonography. The Breast Imagine Reporting and Data System (BI-RADS) grade 4 and 5 patients received biopsy, the women with BI-RADS grade 0 and grade 3 underwent X-ray examination, and those with BI-RADS grade 1 and grade 2 needed follow-up. Results: From Jan. 2012 to Oct. 2017, a total of 184 680 breast cancer examinations were completed at Hami City Hospital, and 149 women were diagnosed as having breast cancer, with a detection rate of 80.68/100 000. A total of 3 203 persons were recommended to undergo breast X-ray examination, and 2 675 persons underwent the examination eventually; 582 persons were advised to acquire the biopsy, and finally all underwent the biopsy. As for the staging results of the breast cancer patients, 36.24% patients were phase 0, 51.00% were phase Ⅰ, 10.07% were phase Ⅱ, and 2.68% were phase Ⅲ. Additionally, 97.31% patients were phase 0,Ⅰ and Ⅱ, and 87.24% were phase 0 and Ⅰ. As for the sensitivity and specificity, 122 (81.88%) breast cancer patients were detected by ultrasound, and 27 (18.12%) patients were detected by X-ray. The detection rate of breast cancer was 8.56/100 000 in the 35-39 age group, was 29.20/100 000 in the 40-50 age group, and 42.71/100 000 in the 51-60 age group. The detection rate of breast cancer in Hui people was significantly higher than that of other ethnic groups (P<0.05), followed by Uygur people. Conclusion: Breast ultrasound screening for breast cancer is easy to carry out in primary hospitals. The compliance of screening subjects in practice is fine, and it is easy to be popularized. It has achieved certain results in the detection rate and early diagnosis of breast cancer. It is an optional breast cancer screening model that is in line with China's national conditions.

Key words: Breast cancer, Ultrasonography, Screening mode, Diagnosis