Abstract: Computed tomography colonography (CTC) is a well-established technique for evaluation of colorectal cancer (CRC). Significant advances have been made in the technique of CTC since its inception. Besides being an excellent tool for detection of CRC, it is minimally invasive, less time-consuming and well tolerated by patients. Furthermore, it has fewer complications than conventional colonoscopy (CC) or barium enema (BE). The application of new technologies, such as electronic cleansing (EC) and dual-energy CT (DECT), enriches the examination of CTC. In 2005, a standardized reporting scheme, “CT colonography reporting and data system (C-RADS)”, was put forward by the working group on virtual colonoscopy. They proposed that the report should include lesion size, number, morphology, location, attenuation and recommendations for lesion surveillance. New research progress and clinical applications of CTC in CRC are reviewed in this article. In addition, the paper also briefly touches upon technique, indications, contraindications, safety and risk of CTC.

Key words: Computed tomography colonography, Colorectal cancer, Computed tomographic colonography reporting and data system, Electronic cleansing, Dual-energy CT